My employer is moving to new location in the same city. Do I (or my employer) need to inform USCIS?
------------- if your employer is GC holder then he need to file AR11, if he is US Citizen then no need.
My I-140 is approved and I am waiting for I-485.
------------- if you move file form AR11 and update your new address with NCSC1800 and provide the reciept# of I-485, A# DOB and new address and also update the service center by sending letter