If you've applied for an I-485 for your wife, her F1 status will be gone, but still under AOS status (it means she is not out of status. she is fine.). Note: only H4 or L4 will still be valid if they apply for I-485 for their spouses.
So once she is under AOS status, if she needs to work, she will have to use her EAD. If she needs to travel, she needs her valid AP before she departs USA, not after she departs. After she gets her valid AP, she can travel if she wants and I think she can get her H4 stamp at US consulate or US embassy (not sure) because what if your I-485 is denied and your status is still H1 (unexpired H1) and your wife's status is AOS status (F1 is no longer valid). If your I-485 is denied, you are still on H1 status, but your wife will be out of status because she doesn't have f1 status or h4 status so I think getting H4 stamp after you get valid AP would be better (but not sure. talk to your lawyer or wait for answers from other people).
Hope this helps.