Visiting India H1B-COS Applied

Hi, I’m on L1 visa and applied for H1B( Cos-regular) this year.
I’m currently waiting for my approval. I want to know that is it possible that I can travel to India for couple of weeks before I get my approval which is expected to come in October.If not,then what will be the best time for the same.

Also my wife is on L2 and her company has applied general H1B visa for her so can she also travel to India before she gets her approval.