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This is really a very frequent question on this board. Most of the people do not like the answers they are getting.
There is nothing you can do to be \'safe.\' Theoretically if you did not have the intention to work indefinitively for the sponsoring company at the time of approval then you commited immigration fraud. I do not think that this type of cases are prosecuted often, look on this discussion group for rescission and you will find a short thread where I tried to gather some information.
You may be safer if you can put together documentation to show that the intent to leave was triggered by an event after the approval.
The implications is that you can be deported at any time in your future. If you happen to be friend with Joe and Joe happens to commit a crime and the INS really wants to come after you then you just gave them a reason by posting your intent on a public forum. Don\'t even bother leaving the sponsoring company now.
It really bothers me when people who spent so much time getting their GC all the sudden just drop all caution and run lose.
Just my 2 cents, I am not a lawyer.