Visit Visa Validity? Can they Re-enter?

sfsf

Registered Users (C)
My parents have 10 years valid visit visa. This is their third visit in four years.

We filed for their permanent residence by filing form I-130 (Nebraska Service Center) which might/will take about two years to process and approve.
We did not file AOS(I-485) and Advance Parole (I-131).

Can they leave the US and enter again as they have valid Visit Visa's?

Please advise.
 
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