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You\'ll not be out of status. However, you will not be able to work between the date of the lay-off and the date your EAD arrives.
If you have H1 now, then that H1 is terminated the moment you are laid off. You are still in status, since after filing I-485 you are considered "an adjustee".
If RFE is for an employment letter, you may have a problem.
You\'ll basically have two options:
1) ask your old employer (the one who sponsored LC and I-140) to write you a letter stating that a job offer is still available to you and that they are willing to re-hire you once your GC is approved.
2) find another employer who can give you a substantially similar position to that which was used for LC and I-140. Then ask this new employer for a letter and send it to INS as an RFE response indicating that you are using the AC-21 rule.
Of course, consulting a lawer is a good idea in your case, no matter what you do.