Medical is valid for 1 year from the date you take your Medial to the date you file your I485. That means if you have already applied for I-485 along with the Medical, it will never expire.
PKLAL is almost correct. Medical exams are valid unless INS asks you to go for medical exam again. Only thing that is required is that you need to file i-485 within a specific time period after completing your medical exam.
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