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I think you can. In the past this used to be a problem with the situation where in you apply for EAD and go to India and return after your EAD approved. This was a problem since you went out on H1/H4 (presumably) but when you return, the status has changed since EAD has been approved.
INS subsequently clarified that it is ok to travel on H1/H4 visa as long as it is valid, irrespective of EAD application status.
Disclaimer: I am not a lawyer. The info provided is my opinion and not truth.