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Hyaluronic Acid: Naturally produced in the human body, this derma filler is safe for use as a Lips Enhacer, for filling fine lines around the eyes and lips, and can be used for fairly deep wrinkles.Lipsation Some of the products that use hyaluronic acid are Restylane and Juvederm. Because it is a natural substance, when the body absorbs it, there are no adverse effects. The average time for sustained results is six months.