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First of all, one has to be cautious. One negative aspect of self-medication with herbal supplements is the fact that some Alpha ZXT products have been shown to counteract the effects of prescription and over-the-counter medications. For example, in 2001, Dr. Piscitelli from the National Institute of Health (NIH) showed a significant drug interaction between St. John's wort (hypericum perforatum), an herbal product sold as a dietary supplement, and Indinavir, a protease inhibitor used to treat HIV infection. The herb has also caused negative interactions with cancer chemotherapeutic drugs and with birth control drugs. http://www.supplements4help.com/is-alpha-zxt-scam-or-fake/